Castaneda and colleagues used a Cox statistical model to compare all-cause death or inpatient COPD exacerbation within one year. They also matched patients taking NBZRAs with those taking no hypnotic drugs. They matched patients receiving NBZRAs and other hypnotics on 40 variables, such as demographics, medical and sleep disorders, and COPD severity.

Among the other hypnotics were melatonin, ramelteon (Rozerem), trazodone (Desyrel, Oleptro) and doxepin (Silenor, SINEquan). To tease out the role of NBZRAs, the researchers designed a study that used thousands of medical records from the Veterans Health Administration to compare the risk of death or inpatient exacerbations for COPD patients who were given new prescriptions for NBZRAs with patients given other drugs that were hypnotics but were not NBZRAs. This can be a confounding factor given that insomnia itself is associated with these risks for COPD patients.” “While multiple observational studies have shown this to be the case, these studies have lacked an active comparator-another class of drugs to compare with NBZRAs. “While frequently used to treat insomnia, NBZRAs are associated with respiratory depression and even death in patients with COPD,” said lead author Jason Castaneda, MD, internal medicine resident, University of Washington, Seattle. When compared to those without hypnotic drug prescriptions, however, the researchers found a greater risk of death or exacerbations. Newswise - ATS 2023, Washington, DC – Chronic obstructive pulmonary disease patients newly prescribed non-benzodiazepine benzodiazepine receptor agonists (NBZRAs) such as zolpidem (Ambien, Intermezzo and other brands), a class of hypnotic drugs prescribed for insomnia, did not have an increased risk of exacerbations requiring hospitalizations or of death than those prescribed other types of hypnotics, according to research published at the ATS 2023 International Conference. ET, Tuesday, Location: Marriott Marquis Washington, Independence Ballroom, Salons E-H (Level M4) Session: C98, Risky Business: Predicting Consequences of OSA Date and Time: 2:51 p.m. All the ideas are there to be yours because everyone else is asleep.EMBARGOED UNTIL: 2:51 p.m., ET, Tuesday, May 23, 2023 “Nighttime is really the best time to work. “A little insomnia is not without its value in making us appreciate sleep, in throwing a ray of light upon that darkness.”― Marcel Proustĩ2. “How do people go to sleep? I’m afraid I’ve lost the knack.” ― Dorothy Parker Quotes About Insomnia “When I feel well and in a good humor, or when I am taking a drive or walking after a good meal, or in the night when I cannot sleep, thoughts crowd into my mind as easily as you could wish.” ― Wolfgang Amadeus Mozartĩ0. “Do you know that awesome feeling when you get into bed, fall right asleep, stay asleep all night and wake up feeling refreshed? Me neither.” - UnknownĨ9. “His impatience for sleep often frightened that very sleep away.” ― Hugh HoweyĨ8. The more I’m awake, the more I see, and the harder to sleep.” ― Donna Lynn HopeĨ7. “Sleep is like the tide only this time the moon doesn’t bring it in.” ― I Need You CasĨ6. I’ve come to talk with you again.” ― Paul SimonĨ5. “Insomnia is only mind over mattress.” - Jane AceĨ4.

“Sleeplessness comes when my thoughts outweigh the night.” - Terri GuillemetsĤ2. Like, that takes me 4 hours, 600 position changes, and a sacrifice to the sleep gods.” - Unknown Inspiring Insomnia QuotesĤ1. “I hate people who can go to sleep as soon as they close their eyes. “Nothing is louder than overthinking after midnight.” - UnknownĤ0. In the morning, I can’t wake up.” - Unknownģ9. “The worst things: to be in bed and sleep not, to want for one who comes not, to try to please and please not.” - Proverbsģ8. “It is a special kind of homelessness to be evicted from your dreams.” - Karen Russellģ7. But then it would be tomorrow, so I decide that no matter how tired, no matter how incoherent I am, I can skip on hour more of sleep and live.” - Sylvia Plathģ6. “I wonder why I don’t go to bed and go to sleep. “It is better to sleep on things beforehand than lie awake about them afterward.” - Baltasar Gracianģ5.

Insomnia quotes